the outcomes

Publications


Borghesani, V., Narvid, J., Battistella, G., Shwe, W., Watson, C., Binney, R., Sturm, V., Miller, Z., Mandelli, M.L., Miller, B., Gorno-Tempini, M.L. (2019) "Looks familiar, but I do not know who she is”: The role of the anterior right temporal lobe in famous face recognition. [accepted in Cortex]

Looking at a face, have you ever had the feeling you know someone but cannot remember they name or personal details? Thanks to three carefully designed experimental task we investigate the neural correlates of name retrieval, semantic information association, and familiarity judgment in a large population of healthy controls and patients with neurodegenerative diseases. Our finding suggest that while naming and semantic association rely on the integrity of the left anterior temporal lobe, the right anterior temporal lobe is crucial for familiarity judgment.

Borghesani, V., Buiatti, M., Eger, E., & Piazza, M. (2018). Conceptual and Perceptual Dimensions of Word Meaning Are Recovered Rapidly and in Parallel during Reading. Journal of cognitive neuroscience, 1-14. [PDF]

In this MEG experiment, we investigated whether perceptual and conceptual dimensions of word meaning are associated to different temporal dynamics. We compared one conceptual dimension (semantic category) and two perceptual dimensions (one concerning a visual feature - the implied real world size, and one concerning an auditory feature – prototypical sound). Our results indicate an automatic, rapid and essentially simultaneous recovery of information along both perceptual and conceptual dimensions of word meaning. However, the three different dimensions appear to dissociate in terms of the brain dynamics involved (changes in phase coherence vs spectral power) and the corresponding underlying sources.


Borghesani, V., de Hevia, M. D., Viarouge, A., Chagas, P. P., Eger, E., & Piazza, M. (2018). Processing number and length in the parietal cortex: Sharing resources, not a common code. Cortex. [PDF]

Ten is more than seven. And 5 cm are more than 3 cm. How similar are the neural processes in action to perform these comparisons? Univariate analysis of fMRI data suggest that both numerical and spatial magnitude comparisons recruit a bilateral occipito-parietal network. However, multivariate analysis indicate that the underlying representational content differ. Thus numerical and spatial magnitudes appear to share common neural resources, yet not a common neural code.

Borghesani, V., Pedregosa, F., Buiatti, M., Amadon, A., Eger, E., & Piazza, M. (2016). Word meaning in the ventral visual path: a perceptual to conceptual gradient of semantic coding. NeuroImage, 143, 128-140. [PDF]

In this fMRI experiment we tested the hypothesis that perceptual and conceptual dimensions of word meaning are coded in different brain regions: perceptual dimension in unimodal perceptual areas, conceptual dimension in heteromodal association areas. We tested the presence of a mapping between a perceptual dimension (implied real object size) and two conceptual dimensions (taxonomic categories at different levels of specificity), and the patterns of brain activity recorded in six areas along the ventral occipito–temporal cortical path. Combining multivariate pattern classification and representational similarity analysis, we found that the visual-perceptual dimension appears to be primarily encoded in early visual regions, while the conceptual dimension in more anterior temporal regions. This anteroposterior gradient of information content, from perceptual to conceptual, indicates that different areas along the ventral stream encode complementary dimensions of the semantic space.

Other Published works:

Borghesani, V., & Piazza, M. (2017). The neuro-cognitive representations of symbols: the case of concrete words. Neuropsychologia, 105, 4-17. [PDF]

Borghesani*, V., de Hevia*, L., Viarouge*, A., Pinheiro Chagas, P., Eger, E., & Piazza, M. (2016). Comparing magnitudes across dimensions: a univariate and multivariate approach. International Workshop on Pattern Recognition in Neuroimaging (pp. 1-4). [PDF]

Borghesani, V., Pedregosa, F., Eger, E., Buiatti, M., & Piazza, M. (2014). A perceptual-to-conceptual gradient of word coding along the ventral path. International Workshop on Pattern Recognition in Neuroimaging (pp. 1-4). [PDF]


Under review

Borghesani, V., Monti, A., Fortis, P., & Miceli, G. (under review) Monothematic spatial delusion: A review on reduplicative paramnesia for places and a case report.

Borghesani, V., Riello, M., Monti, A., & Gorno-Tempini, M. (under review) Investigating the Neural Representations of Movement across Semantic Categories: the Role of the Left Fronto-Parietal Network.

Vigano, S., Borghesani, V., & Piazza, M. (under review) How learning novel object concepts changes the brain circuits for memory and perception

Battistella, G., Henry, M., Gesierich, B., Wilson, S.M., Borghesani, V., Shwe, W., Miller, Z., Deleon, J., Bruce, M., Jovicich, J., Papinutto, N., Seeley, W.W. Mandelli, M.L., & Gorno-Tempini, M.L. (under review) Differential intrinsic functional connectivity changes in three language networks in Semantic Primary Progressive Aphasia.

Caso, F., Agosta, F., Magnani, G., Cardamone, R., Borghesani, V., Miller, Z., Riva, N., Coppola, G., Seeley, W. , Miller, B., Gorno-Tempini, M.L. , & Filippi, M. (under review) Two cases of semantic variant of primary progressive aphasia due to C9orf72 hexanucleotide repeat expansion


In preparation

Borghesani, V., Hinkley, L.B., Ranasinghe, K., Thompson, M., Shwe, W., Mizuiri, D., Honma, S., Houde, J.F., Miller, Z., Nagarajan, S.S., & Gorno-Tempini, M.L. (in prep) Taking the sub-lexical route: the spatiotemporal dynamics of reading in semantic variant of Primary Progressive Aphasia.

Borghesani, V., Battistella, G., Mandelli, M., Miller, Z., & Gorno-Tempini, M.L. (in prep) TDP-43-C pathology and frontotemporal degeneration: lessons learned from a bilateral parcellation of the anterior temporal lobe.

Vonk, J., Borghesani, V., Battistella, G., Welch, A., Hubbard, I., Mandelli, M., Miller, Z., & Gorno-Tempini, M.L. (in prep) It’s not just semantics: nine-year evolution of an early case of right anterior temporal degeneration


Posters & Talks

Borghesani, V., Hinkley, L.B., Ranasinghe, K., Thompson, M., Shwe, W., Mizuiri, D., Honma, S., Houde, J.F., Miller, Z., Nagarajan, S.S., & Gorno-Tempini, M.L. (2018) Taking the sub-lexical route: the spatiotemporal dynamics of reading in semantic variant of Primary Progressive Aphasia. SfN, Society of Neuroscience

Borghesani, V., (2017) Helping the quest for language in the brain. Science Hack Day - San Francisco

Borghesani, V., de Hevia*, L., Viarouge*, A., Pinheiro Chagas, P., Eger, E., & Piazza, M. (2016).Comparing magnitudes across dimensions: a univariate and multivariate approach. PRNI, International Workshop on Pattern Recognition in Neuroimaging

Borghesani, V., de Hevia*, L., Viarouge*, A., Pinheiro Chagas, P., Eger, E., & Piazza, M. (2016). Few: Many = Short: Long? Coding Of Magnitude Across Different Quantitative Dimensions. CAOS, Concepts, Actions, Objects

Borghesani, V., Eger, E., Buiatti, M., & Piazza, M. (2015) Perceptual and conceptual semantic dimensions: where and when? SNL, Society for the neurobiology of language

Borghesani, V., Eger, E., Buiatti, M., & Piazza, M. (2015) Can you see what I mean? Perceptual and conceptual semantics during words reading. SfN, Society of Neuroscience

Borghesani, V., Pedregosa, F., Eger, E., Buiatti, M., & Piazza, M. (2014) A perceptual-to-conceptual gradient of word coding along the ventral path. PRNI, International Workshop on Pattern Recognition in Neuroimaging [selected for oral presentation]

Borghesani, V., Pedregosa, F., Eger, E., Buiatti, M., & Piazza, M. (2014) Word reading in the ventral stream: A perceptual to conceptual gradient of information coding. CAOS, Concepts, Actions, Objects [selected for oral presentation and winner of the best poster award]


Theses

PhD thesis: Thesis committee: Christophe Pallier (advisor), Manuela Piazza (advisor), James Haxby (reviewer), Rik Vandenberghe (reviewer), Laurent Cohen (examiner), Marius Peelen (examiner). “The Neuro-Cognitive Representation of Word Meaning Resolved in Space and Time. [PDF]

Master thesis: a single case study on the neuropsychological substrate of reduplicative paramnesia (supervisor dott.ssa Alessia Monti PhD). In Italian: “Analisi neuropsicologica della paramnesia reduplicativa per i luoghi: stato dell’arte e studio di un caso”. [PDF]

Bachelor thesis: a tDCS study investigating the role of dorsolateral prefrontal cortex in cognitive dissonance (supervisor Prof. G. di Pellegrino MD, PhD). In Italian: “Il ruolo della corteccia dorsolaterale prefrontale nella dissonanza cognitiva”. [PDF]